Oxidative stress has a fundamental role in the development of complications of diabetes through its negative impact on the heart and blood vessels. This induces metabolic disorders of diabetes mellitus and overproduction of mitochondrial superoxide in the endothelial cells of large and small vessels, leading to impaired diastole. Vasodilation dysfunction is the major pathological change of blood vessels in diabetes mellitus and the pathological basis of diabetic vascular complications, as well as atherosclerosis and other cardiovascular diseases. Studies have shown that pomegranate flower polyphenols (PFP) extract is an effective antioxidant that possesses hypoglycemic effects and anti-inflammatory properties. In addition, PFP exhibits vasodilation effects on vascular endothelium in diabetic rats through inhibiting endothelial-derived contracting factors, such as endothelin-1, angiotensin II, and thromboxane B2, and increasing 6-keto-PGF1a concentrations in plasma. Here, we aimed to present the ability of PFP antioxidants to reduce the effect of oxidative stress and significantly improve diastolic relaxation in rats with hyperglycemia. Therefore, in addition to treating diabetes, the use of antioxidants to reduce the negative effects of oxidative stress has many therapeutic benefits.

·    More than 23 years’ experience in health education and healthcare service overseas.

·    Certificate of New Zealand International Qualification Assessment (IQA).

·    New Zealand Permanent Resident with New Zealand TD Passport.

·    High-End Foreign Experts-China.

·    High-End Foreign Experts-Malaysia.

·    Valid Malaysian APC (Annual Practicing Certificate) and teaching permit.

·    Residence Pass-Talent (RP-T) in Malaysia.

·    Chosen for Who’s Who in Medicine and Healthcare 2009/2010.

·    Overseas full practicing certificate to practice and teach medicine.

·    Language: English and Chinese.

·    Have published more than 50 research papers in SCI Journals, and written a book on diabetes.

Education

·    PhD Degree in Medicine, Wuhan University, Wuhan, China. 2012.

·    Master Degree in Medicine, Wuhan University, Wuhan, China. 2008.

Career

·    Honorary Professor and External Advisor from New Zealand, Widad University College, Malaysia                           

·    Associate Professor and High-end Foreign Expert, College of Medicine, Chengdu University, China.  

·    High-end Foreign Expert and faculty member, Medical College, SEGi University, Malaysia.                                                            

·    High-end Foreign Expert and faculty member, Medical College, Asia Metropolitan University, Malaysia.                                    

        Research

·       Experienced and passionate about basic and clinical research, research has been focused on genetic susceptibility to allergic/ autoimmune related diseases, also acupuncture, holistic and botanical medicine research. 

·       Published more than 50 papers in Scientific Journals and written a section of a book on diabetes